| dc.creator | Kibuka, musoke | |
| dc.creator | Mukkaanya, Moses E | |
| dc.date | 2013-07-02T08:18:35Z | |
| dc.date | 2013-07-02T08:18:35Z | |
| dc.date | 1975-01 | |
| dc.date.accessioned | 2018-09-04T12:50:07Z | |
| dc.date.available | 2018-09-04T12:50:07Z | |
| dc.identifier | | |
| dc.identifier | http://hdl.handle.net/10570/1461 | |
| dc.identifier.uri | http://hdl.handle.net/10570/1461 | |
| dc.description | A dissertation submitted for the award of the degree of Master of Medicine in Paediatrics of Makerere University | |
| dc.description | Seventy-two patients with proved haemoglobin SS were studied in respected of their haemoglobin, reticulocyte counts, serum bilirubin and their Glucose-6-phosphate dehydrogenase values in international units per gram of Haemoglobin. Of the whole group 18% were found to be deficient in the enzyme. A retrospective study of these patients was carried out to see if those who were deficient in the enzyme are those who experienced haemolytic crises. Records at the Sickle Cell Clinic did not reveal any well documented case of a haemolytic crisis having occurred in any of these patients, a few had clinical evidence of increased haemolysis. One patient who had evidence of increased haemolysis was discussed in detail and was thought to be Glucose-6-Phosphate Dehydrogenase deficient, and it was suggested that the increased haemolysis was precipitated by ingestion of aspirin. It has been suggested that a detailed study if those patients was Sickle Cell anaemia and Glucose-6-Phopsphate Dehydrogenase deficiency is required to establish the occurrence of haemolytic crises and find the precipitating factors. | |
| dc.language | en | |
| dc.subject | Haemolytic crises | |
| dc.subject | Hemolytic anemia | |
| dc.subject | Sickle cell anemia | |
| dc.subject | Red cells | |
| dc.subject | Red cell enzyme | |
| dc.subject | Erythrocytes | |
| dc.subject | Glucose-6-phosphate dehydrogenase | |
| dc.subject | Glucose-6-phosphate dehydrogenase deficiency | |
| dc.subject | Hemoglobin | |
| dc.title | The relationship between the haemolytic crises in sickle cell anaemia, and the deficiency of the red cell enzyme glucose-6-phosphate dehydrogenase | |
| dc.type | Thesis, masters | |
