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dc.creatorMugerwa, R. D.
dc.date2013-01-09T07:04:13Z
dc.date2013-01-09T07:04:13Z
dc.date1974
dc.date.accessioned2018-09-04T12:33:00Z
dc.date.available2018-09-04T12:33:00Z
dc.identifierhttp://hdl.handle.net/10570/960
dc.identifier.urihttp://hdl.handle.net/10570/960
dc.descriptionA dissertation submitted in partial fulfillment of the requirements for the award of the Degree of Master of Medicine of Makerere University
dc.descriptionFifty homozygous sicklers and ten heterozygous sickle cell patients selected from the Sickle Cell Clinic, Cardiac Clinic and inpatients on the medical wards of Mulago Hospital form the basis of this dissertation. It starts with a historical review and pathology of sickle cell disease. Cardiovascular alterations in anaemia with emphasis on physiological and pathological considerations in sickle cell disease are discussed. The findings among the patients studied are described dwelling mainly on presenting symptoms, cardiovascular findings notably cardiomegally, murmurs, abnormal heart sounds, electro-cardiographic and x-ray abnormalities. A discussion of findings with reference to work on the same subject by other writers is presented. Some of the possible haemo-dynamic alterations in sickle cell disease are outlined and a need for further elaborate studies in this condition is stressed.
dc.languageen
dc.subjectSickle cells
dc.subjectSickle cell disease
dc.subjectSickle cell patients
dc.subjectSicklers
dc.subjectCardiovascular alterations
dc.subjectCardiomegally
dc.subjectAbnormal heart sounds
dc.subjectMulago hospital
dc.titleCardiovascular findings in patients with sickle cell disease
dc.typeThesis, masters


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