| dc.creator | Nalwoga, H. | |
| dc.creator | Odida, M. | |
| dc.creator | Wabinga, H. | |
| dc.date | 2013-02-20T08:25:25Z | |
| dc.date | 2013-02-20T08:25:25Z | |
| dc.date | 2006-08 | |
| dc.date.accessioned | 2018-09-04T12:33:02Z | |
| dc.date.available | 2018-09-04T12:33:02Z | |
| dc.identifier | Nalwoga, H., Odida, M., & Wabinga, H. (2006). c-erb-2 oncoprotein over-expression in breast cancer and its relationships to histology type and grade in a Uganda population. East African Medical Journal. 83(8): 63-68 | |
| dc.identifier | | |
| dc.identifier | http://hdl.handle.net/10570/1104 | |
| dc.identifier.uri | http://hdl.handle.net/10570/1104 | |
| dc.description | Objective: To evaluate c-erbB-2 oncoprotein over expression in breast cancer patients of Kyadondo county and also relate this oncoprotein to histological type and grade of the tumour. Design: Cross-sectional study. Setting: Pathology Department, Faculty of Medicine, Makerere University. Subjects: Seventy two breast cancer patients who were among the 174 entered in survival study had their paraffin breast tissue blocks retrieved from archives of Pathology Department and had their c-erbB-2 determined by peroxidase-labeled streptavidin-biotin immunohistochemical method. Results: c-erbB-2 oncoprotein was over expressed in 33.3% of the tumours and correlated positively with histological grade (p = 0.007). TH oncoprotein over expression was not restricted to any particular histological type and there was no association with age of patient. Conclusion: The over expression of c-erbB-2 oncoprotein observed in one third of breast cancer patients of this African population could partly explain the observed poor survival rate reported in this community. | |
| dc.language | en | |
| dc.publisher | East African Medical Journal | |
| dc.subject | Uganda | |
| dc.subject | Breast cancer | |
| dc.title | c-erb-2 oncoprotein over-expression in breast cancer and its relationships to histology type and grade in a Uganda population | |
| dc.type | Other | |
