| dc.creator | Sacktora, Ned C. | |
| dc.creator | Wong, Matthew | |
| dc.creator | Nakasujja, Noeline | |
| dc.creator | Skolasky, Richard L. | |
| dc.creator | Selnes, Ola A. | |
| dc.creator | Musisi, Seggane | |
| dc.creator | Robertson, Kevin | |
| dc.creator | McArthur, Justin C. | |
| dc.creator | Ronald, Allan | |
| dc.creator | Katabira, Elly | |
| dc.date | 2011-12-15T16:55:05Z | |
| dc.date | 2011-12-15T16:55:05Z | |
| dc.date | 2005 | |
| dc.date.accessioned | 2018-09-04T12:32:19Z | |
| dc.date.available | 2018-09-04T12:32:19Z | |
| dc.identifier | Sacktora, N. ,Wong, M.,Nakasujja, N., e tal. The International HIV Dementia Scale: a new rapid screening test for HIV dementia Vol 19 No 13 | |
| dc.identifier | 0269-9370 | |
| dc.identifier | 1473-5571 | |
| dc.identifier | http://hdl.handle.net/10570/257 | |
| dc.identifier.uri | http://hdl.handle.net/10570/257 | |
| dc.description | Objective: HIV dementia is an important neurological complication of advanced HIV infection. The use of a cross-cultural screening test to detect HIV dementia within the international community is critical for diagnosing this condition. The objective of this study was to evaluate the sensitivity and specificity of a new screening test for HIV dementia, the International HIV Dementia Scale (IHDS) in cohorts from the US and Uganda. Design: Two cross-sectional cohort studies designed to evaluate for the presence of HIV dementia. Methods: Sixty-six HIV-positive individuals in the US and 81 HIV-positive individuals in Uganda received the IHDS and full standardized neurological and neuropsychological assessments. The sensitivity and specificity of varying cut-off scores of the IHDS were evaluated in the two cohorts. Results: In the US cohort, the mean IHDS score for HIV-positive individuals without dementia and with dementia were 10.6 and 9.3 respectively (P < 0.001). Using the cutoff of 10, the sensitivity and specificity for HIV dementia with the IHDS were 80% and 57% respectively in the US cohort, and 80% and 55% respectively in the Uganda cohort. Conclusions: The IHDS may be a useful screening test to identify individuals at risk for HIV dementia in both the industrialized world and the developing world. Full neuropsychological testing should then be performed to confirm a diagnosis of HIV dementia. | |
| dc.language | en | |
| dc.publisher | Lippincott Williams & Wilkins | |
| dc.subject | HIV | |
| dc.subject | Dementia | |
| dc.subject | Screening test | |
| dc.subject | Uganda | |
| dc.subject | International | |
| dc.subject | Scale | |
| dc.title | The International HIV Dementia Scale: a new rapid screening test for HIV dementia | |
| dc.type | Journal article, peer reviewed | |
